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Which structure is the large band of neural fibers connecting the two cerebral hemispheres?

Anterior commissure

Corpus callosum

Interhemispheric communication is carried by commissural fibers, and the largest of these is the corpus callosum. This broad, C-shaped bundle sits beneath the cerebral cortex and links homologous areas across the two hemispheres, enabling coordinated activity and integration of sensory, motor, and cognitive information.

The anterior commissure is a much smaller bundle that primarily connects portions of the temporal lobes and olfactory regions, not the entire cortex. The posterior commissure is a small tract near the top of the midbrain involved in certain reflex pathways, not a major conduit for cortical cross-talk. The fornix is a limbic system tract connecting the hippocampus to the mammillary bodies and other limbic structures, not linking the hemispheres.

Posterior commissure

Fornix

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